Complement Map Database

The complement system is a central component of innate immunity and important for cellular integrity and tissue homeostasis. Complement Map Database (CMAP) is a unique repository focused on documented molecular interactions described within the complement cascade and between complement and other biological systems. Information contained in CMAP is entirely based on published experimental data and is fully revised by experts in the field. Each connection is hyperlinked to publication sources the analytical methods used for describing the interaction.

Main Map --- direct intractions between complement components and other endogenous/exogenous molecules Interplay between the complement and coagulation networks Complement evasion by Staphylococcus aureus The crosstalk between the complement system and Toll-like receptor (TLR) signaling pathways Roles of complement in cancer
	CMAP Project The complement system is a central component of innate immunity and important for cellular integrity and tissue homeostasis. Complement Map Database (CMAP) is a unique repository focused on documented molecular interactions described within the complement cascade and between complement and other biological systems. Information contained in CMAP is entirely based on published experimental data and is fully revised by experts in the field. Each connection is hyperlinked to publication sources the analytical methods used for describing the interaction.		Please Cite Us Yang K, Dinasarapu AR, Reis ES, Deangelis RA, Ricklin D, Subramaniam S, Lambris JD. CMAP: Complement Map Database. Bioinformatics 2013 Jun 4 About Our Team CMAP is developed and maitained by the research group of Professor John D. Lambris at the University of Pennsylvania. Our major research interests are investigating the various aspects of innate immunity, and particularly the complement system, in health and disease. see more